Fig. 2. Homologous protein structure of SMS family members with a sterile alpha motif (SAM) and putative transmembrane (1-6) domains and total amino acid number [1]. Information on genes, proteins and domains originates from GeneCards(r) Human Gene Database, UniProtKB [Q86VZ5 (SMS1_HUMAN); Q8NHU3 (SMS2_HUMAN); Q96LT4 (SAMD8_HUMAN)] and [10].